RAPID-AMS

Randomised evaluation of RADIX

We will build three sequential research protocols within the same patient population for the same ultimate goal of better antibiotic prescribing.

Each stage seeks to demonstrate better prescribing by providing information at the time of prescribing on

1. Local antibiotic guidelines

2. Historical anti-microbial resistance

3. Predicted anti-microbial resistance

Stage	Population	Intervention	Comparator	Outcome
1	Urinary Tract Infection	Nudge to guideline compliance	Usual care	Guideline compliant prescribing
2	Urinary Tract Infection	Bug-drug mismatch alert based on historical antimicrobial resistance	Stage 1 Intervention	Reduced bug-drug mismatch against historical samples
3	Urinary Tract Infection	Bug-drug mismatch alert based on predicted antimicrobial resistance	Stage 2 Intervention	Reduced bug-drug mismatch against current samples